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synthesis 2 [syntheses, -pl ]syntheses, -pl ] - translation to
![Vitamin B<sub>12</sub> total synthesis]]: [[Retrosynthetic analysis]]''' of the Woodward–Eschenmoser total synthesis that was reported in two variants by these groups in 1972. The work involved more than 100 PhD trainees and postdoctoral fellows from 19 different countries. The [[retrosynthesis]] presents the disassembly of the target vitamin in a manner that makes chemical sense for its eventual forward construction. The target, Vitamin B<sub>12</sub> ('''I'''), is envisioned being prepared by the simple addition of its tail, which had earlier been shown to be feasible. The needed precursor, [[cobyric acid]] ('''II'''), then becomes the target and constitutes the "[[corrin]] core" of the vitamin, and its preparation was envisaged to be possible via two pieces, a "western" part composed of the A and D rings ('''III''') and an "eastern" part composed of the B and C rings ('''IV'''). The restrosynthetic analysis then envisions the starting materials required to make these two complex parts, the yet complex molecules '''V'''–'''VIII'''.](https://commons.wikimedia.org/wiki/Special:FilePath/VitaminB12 retrosynthesis.svg?width=200 "Vitamin B<sub>12</sub> total synthesis]]: [[Retrosynthetic analysis]]''' of the Woodward–Eschenmoser total synthesis that was reported in two variants by these groups in 1972. The work involved more than 100 PhD trainees and postdoctoral fellows from 19 different countries. The [[retrosynthesis]] presents the disassembly of the target vitamin in a manner that makes chemical sense for its eventual forward construction. The target, Vitamin B<sub>12</sub> ('''I'''), is envisioned being prepared by the simple addition of its tail, which had earlier been shown to be feasible. The needed precursor, [[cobyric acid]] ('''II'''), then becomes the target and constitutes the \"[[corrin]] core\" of the vitamin, and its preparation was envisaged to be possible via two pieces, a \"western\" part composed of the A and D rings ('''III''') and an \"eastern\" part composed of the B and C rings ('''IV'''). The restrosynthetic analysis then envisions the starting materials required to make these two complex parts, the yet complex molecules '''V'''–'''VIII'''.")
![Two schoolboys in [[Chittagong]], [[Bangladesh]]](https://commons.wikimedia.org/wiki/Special:FilePath/Muslim Schoolboys - Chittagong - Bangladesh (13058130525).jpg?width=200 "Two schoolboys in [[Chittagong]], [[Bangladesh]]")
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Ex: The application of the classification schemes, once constructed, involves synthesis, or the drawing together of the single concepts which are listed in the scheme from their different facets, in order to specify compound subjects.
Βικιπαίδεια
Total synthesis is the complete chemical synthesis of a complex molecule, often a natural product, from simple, commercially-available precursors. It usually refers to a process not involving the aid of biological processes, which distinguishes it from semisynthesis. Syntheses may sometimes conclude at a precursor with further known synthetic pathways to a target molecule, in which case it is known as a formal synthesis. Total synthesis target molecules can be natural products, medicinally-important active ingredients, known intermediates, or molecules of theoretical interest. Total synthesis targets can also be organometallic or inorganic, though these are rarely encountered. Total synthesis projects often require a wide diversity of reactions and reagents, and subsequently requires broad chemical knowledge and training to be successful.
Often, the aim is to discover a new route of synthesis for a target molecule for which there already exist known routes. Sometimes, however, no route exists, and chemists wish to find a viable route for the first time. Total synthesis is particularly important for the discovery of new chemical reactions and new chemical reagents, as well as establishing synthetic routes for medicinally important compounds.
